Psychiatric treatment in men with prostate cancer ? Results from a ...

Psychiatric treatment in men with prostate cancer ? Results from a Nation-wide, population-based cohort study from PCBaSe Sweden.

Eur J Cancer. 2011 May 23;

Authors: Bill-Axelson A, Garmo H, Nyberg U, Lambe M, Bratt O, Stattin P, Adolfsson J, Steineck G

AIM: To explore whether the self-reported psychological distress among men with prostate cancer was to the extent that it required psychiatric treatment. METHODS: PCBaSe Sweden, a merged database based on the National Prostate Cancer Register including 97% of all prostate cancers registered as well as age-matched controls. We calculated relative risks and 95% confidence intervals to compare risks of psychiatric treatment due to depression, anxiety, and post-traumatic stress disorder controlling for age and socio-economic factors. We used odds ratios to compare use or no use of antidepressants. FINDINGS: In total 72,613 men with prostate cancer and 217,839 men without prostate cancer were included for analyses. Psychiatric hospitalisation due to depression, anxiety and post-traumatic stress disorder were significantly increased (RR 1.29, (95% CI 1.14-1.45), RR 1.42 (95% CI 1.12-1.80) and RR 1.61 (95% CI 1.16-2.24), respectively). However, hospitalisations due to anxiety were only increased in men with more advanced tumours RR 2.28 (95% CI 1.45-3.57). The use of antidepressants was increased for all men with prostate cancer RR 1.65 (95% CI 1.54-1.77) and treatment strategies RR 1.93 (95% CI 1.75-2.13). INTERPRETATION: Men diagnosed with prostate cancer had increased risk of psychiatric treatment for depression, post-traumatic stress disorder and use of antidepressants regardless of risk group and treatment strategy compared to age-matched controls, whilst more advanced prostate cancer was associated with severe anxiety disorders.

PMID: 21612913 [PubMed - as supplied by publisher]

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Source: http://feeds.myptsd.me/2011/05/psychiatric-treatment-in-men-with-prostate-cancer-results-from-a-nation-wide-population-based-cohort-study-from-pcbase-sweden-2/

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